報告題目：Electrokinetic Transport in Micro/Nano-fluidics

報告人：Shizhi Qian（Department of Mechanical and Aerospace Engineering Old Dominion University）

報告時間：2015年7月14日上午9:00

報告地點：18-809

主辦單位：國際交流合作處、科協、航空宇航學院

 

Electrokinetics has emerged as one of the most promising techniques to manipulate fluid, particles and ions in micro/nano-fluidic devices, which have the potential of revolutionizing various bioanalytical applications.

The first half of this talk will be on experimental and numerical studies of electrokinetic particle transport in several types of microfluidic channels, with emphasis on dielectrophoretic (DEP) effect. The numerical predictions are in quantitative agreement with our own and other researchers’ experimental results. It has been found that the DEP effect could be utilized to separate, focus and trap particles in microfluidic devices. DEP particle-particle interactions could assemble and form particle chains parallel to the applied electric field, based on which a microfluidic device has been developed to achieve a high throughput cell electrofusion (Fig.1).

The second half of this talk will present numerical study of electrokinetic fluid and particle transport in nanofluidics. A continuum-based numerical model, which is capable of dynamically tracking the particle translocation through a nanopore with the consideration of the finite electrical double layers adjacent to charged surfaces, has been developed. The predictions on the ionic current change due to the presence of particles inside the nanopore are in qualitative agreement with existing experimental results. Furthermore, various analytical models for ionic conductance and streaming conductance in pH-regulated nanofluidics have been developed and validated by experimental data available from the literature.

Shizhi Qian received his B.S. and first Ph.D. from Huazhong University of Science and Technology, China in 1994 and 1998, respectively. He worked afterwards as a senior engineer in industry for two years. From February 2001 to August 2002 he worked as a Postdoctoral Researcher in Mechanical Engineering and Applied Mechanics (MEAM), University of Pennsylvania (PENN) under the supervision of Professor Haim H. Bau. From September 2002 to December 2004, he pursued another Ph.D with Professor Bau. He was then promoted to Research Associate, and worked at PENN until he became Assistant Professor in the Department of Mechanical Engineering at the University of Nevada Las Vegas (UNLV) in August 2005. He joined the Department of Aerospace Engineering at the Old Dominion University as an Assistant Professor in July 2008 and was promoted as tenured associate professor in July 2011. He was a WCU (World Class University) Fellow in Korea during the period from 2009 to 2014. Since 2002, he has published 130 peer-reviewed journal articles, 5 book chapters, and 81 works in conference proceedings. As of June 2015, ISI Citation Index has shown over 2,000 citations of his work with h-index of 26 (26 articles have been cited at least 26 times).